Thermo Fisher Scientific Neurokinin 1 Receptor Polyclonal Antibody
Neurokinin 1 Receptor를 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응. WB, IHC, ICC, ELISA 등 다양한 응용에 적합. KLH 결합 합성 펩타이드(aa 2-50)로 면역화. 고순도 Protein A 정제, 안정적 액상 형태.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Neurokinin 1 Receptor, amino acids 2–50 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Tachykinin Receptor 1 (TACR1), also known as Neurokinin 1 Receptor, is part of the Tachykinin Receptor subfamily mediating phosphatidylinositol metabolism via substance P. It plays roles in depression, anxiety, stress, behavioral responses, neuronal survival, and cardiovascular and respiratory regulation. It is implicated in rheumatoid arthritis and osteoarthritis progression. Two receptor variants are produced by alternative splicing. Expression is mainly found in brain, blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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