Thermo Fisher Scientific KCTD15 Polyclonal Antibody
Rabbit polyclonal antibody against human KCTD15, validated for WB and ICC/IF. Recognizes amino acids 24–223 of KCTD15. Suitable for detecting KCTD15 expression in human and related species. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 24–223 of Human KCTD15 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.89 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548284 |
Product Specific Information
- Recommended positive controls: NT2D1, IMR32
- Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (88%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Childhood and adult obesity have increased dramatically over the past decade due to environmental and genetic factors. The potassium channel KCTD15 has been identified as a genetic locus associated with higher than normal body mass index (BMI) in humans, along with genes such as GNPDA2, MTCH2, FTO, and TMEM18. Studies on single nucleotide polymorphisms (SNPs) in non-diabetic and diabetic patients showed that FTO was most strongly associated with obesity, while MTCH2 and GNPDA2 were also significantly associated with higher BMI levels. At least two isoforms of KCTD15 are known to exist.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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