Thermo Fisher Scientific ARC Polyclonal Antibody
ARC 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 용액 형태로 제공되며, 단기 4°C, 장기 -20°C 보관이 권장됩니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 1–197 of Human NOL3 (ARC) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547335 |
Product Specific Information
- Recommended positive control: HeLa cells
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
ARC (also known as NOL3 - Nucleolar protein 3) has two isoforms.
- Isoform 1: Involved in RNA splicing.
- Isoform 2: Functions as an apoptosis repressor that blocks multiple modes of cell death.
ARC inhibits extrinsic apoptotic pathways by:
- Interacting with FAS and FADD upon FAS activation, blocking DISC assembly.
- Interacting with CASP8 in a mitochondria localization- and phosphorylation-dependent manner, limiting soluble CASP8 for DISC-mediated activation.
ARC also inhibits intrinsic apoptotic pathways via interaction with BAX, preventing mitochondrial dysfunction and release of pro-apoptotic factors.
Mutations in the gene may result in myoclonus, familial cortical conditions.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific AP3B1 Polyclonal Antibody
660,800원
Thermo Fisher Scientific
Thermo Fisher Scientific PAPSS2 Polyclonal Antibody
660,800원
Thermo Fisher Scientific
Thermo Fisher Scientific ARC Polyclonal Antibody
660,800원
Thermo Fisher Scientific
Thermo Fisher Scientific Cullin 4A Polyclonal Antibody
660,800원
Thermo Fisher Scientific
Thermo Fisher Scientific Cullin 4B Polyclonal Antibody
660,800원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|