원본
Thermo Fisher Scientific ARC Polyclonal Antibody
상품 한눈에 보기
ARC 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 용액 형태로 제공되며, 단기 4°C, 장기 -20°C 보관이 권장됩니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다회원가입 없이 바로 구매하세요
가입하지 않아도 비회원가로 구매하실 수 있습니다.
마지막 업데이트 2025. 08. 01. 오전 08:51
카탈로그 번호 · 상품 설명출고판매가담기
Thermo Fisher Scientific PA529861 ARC Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
660,800원VAT 포함 726,880원
Thermo Fisher Scientific · Thermo Fisher Scientific ARC Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 1–197 of Human NOL3 (ARC) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547335 |
Product Specific Information
- Recommended positive control: HeLa cells
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
ARC (also known as NOL3 - Nucleolar protein 3) has two isoforms.
- Isoform 1: Involved in RNA splicing.
- Isoform 2: Functions as an apoptosis repressor that blocks multiple modes of cell death.
ARC inhibits extrinsic apoptotic pathways by:
- Interacting with FAS and FADD upon FAS activation, blocking DISC assembly.
- Interacting with CASP8 in a mitochondria localization- and phosphorylation-dependent manner, limiting soluble CASP8 for DISC-mediated activation.
ARC also inhibits intrinsic apoptotic pathways via interaction with BAX, preventing mitochondrial dysfunction and release of pro-apoptotic factors.
Mutations in the gene may result in myoclonus, familial cortical conditions.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
Thermo Fisher ScientificThermo Fisher Scientific AP3B1 Polyclonal Antibody660,800원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific PAPSS2 Polyclonal Antibody660,800원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific Cullin 4A Polyclonal Antibody660,800원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific Cullin 4B Polyclonal Antibody660,800원VAT별도
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.