
Thermo Fisher Scientific ARAP1 Polyclonal Antibody
ARAP1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot과 면역세포염색에 적합. 인간, 마우스, 랫트 시료 반응. 항원 친화 크로마토그래피로 정제된 고순도 항체. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human ARAP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720285 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% (by SDS-PAGE).
Target Information
ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeat. This adaptor serves as a link between phosphoinositide-, Arf-, and Rho-mediated cell signaling pathways.
ARAP1 supports plasma membrane recycling of the angiotensin II type 1 receptor (AT1) and is also important for cell-specific trafficking of the pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thereby promoting TRAIL-induced apoptosis in certain cell types. Additionally, ARAP1 influences cell spreading.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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