Thermo Fisher Scientific APBB2 Monoclonal Antibody (2D8)
인간 APBB2 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot과 ELISA에 적합합니다. GST 태그가 결합된 재조합 단백질로 면역화되었으며, PBS(pH 7.4) 용액 형태로 제공됩니다. 알츠하이머 관련 신호전달 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.03 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D8 |
| Immunogen | APBB2 (AAH27946, 1–100 a.a) partial recombinant protein with GST tag (MW of GST tag alone: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MSEVLPADSG VDTLAVFMAS SGTTDVTNRN SPATPPNTLN LRSSHNELLN AEIKHTETKN STPPKCRKKY ALTNIQAAMG LSDPAAQPLL GNGSANIKLV
Target Information
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta precursor protein and amyloid beta precursor-like protein 2.
This protein contains two phosphotyrosine binding domains, which are thought to function in signal transduction.
Polymorphisms in this gene have been associated with Alzheimer’s disease.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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