Thermo Fisher Scientific CDY1B Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 60-320 of human CDY1B (NP_0010038951) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CDY1,uniProtId:Q9Y6F8-1,ncbiNodeId:9606,antigenRange:60-320,antigenLength:540,antigenImageFileName:PA5-90567_CDY1_Q9Y6F8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-90567_CDY1_Q9Y6F8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.46 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806121

Product Specific Information

Immunogen sequence: EKQKKLTWTT TSRIFSNNAR RRTSRSTKAN YSKNSPKTPV TDKHHRSKNR KLFAASKNVR RKAASILSDT KNMEIINSTI ETLAPDSPFD HKTVSGFQKL EKLDPIAADQ QDTVVFKVTE GKLLRDPLSR PGAEQTGIQN KTQIHPLMSQ MSGSVTASMA TGSATRKGIV VLIDPLAANG TTDMHTSVPR VKGGQRNITD DSRDQPFIKK MHFTIRLTES ASTYRDIVVK KEDGFTQIVL STRSTEKNAL NTEVIKEIVN A; Positive Samples: Mouse testis, Rat testis; Cellular Location: Nucleus

Target Information

CDY1 containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.