Thermo Fisher Scientific FOXP3 Monoclonal Antibody (3G3), Alexa Fluor 488
FOXP3 단백질을 인식하는 Alexa Fluor 488 형광 표지 단일클론 항체로 인간 및 마우스 시료에 반응. Flow Cytometry 및 Western Blot에 적합. 조절 T세포 연구용으로 사용되며, 액상 형태로 4°C 암소 보관.
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- pk
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Thermo Fisher Scientific FOXP3 Monoclonal Antibody (3G3), Alexa Fluor 488
Applications
- Western Blot (WB): Assay-dependent
- Flow Cytometry (Flow): 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G3 |
| Immunogen | Full-length His-tagged recombinant murine FoxP3 |
| Conjugate | Alexa Fluor™ 488 |
| Excitation / Emission Max | 499 / 520 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539533 |
Additional Formats
- Unconjugated (MA5-44011)
- Alexa Fluor 647 (MA5-18160)
- APC (MA5-44084)
- PE (MA1-10332)
- Custom conjugation available upon request
Product Specific Information
This antibody recognizes the N-terminal region of FoxP3, a 47–55 kDa intracellular transcription factor that serves as the master regulator in the development and function of regulatory T cells.
Target Information
FOXP3 (Forkhead box protein 3) is a transcriptional regulator belonging to the forkhead/winged-helix family, essential for immune homeostasis. It is highly expressed in CD25+ CD4+ regulatory T cells, and defects in FOXP3 lead to immune dysregulation syndromes such as IPEX (X-linked autoimmunity-allergic dysregulation). FOXP3 expression can be modulated by p53 in response to DNA damage and is considered a key marker for regulatory T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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