Thermo Fisher Scientific TRIP15 Polyclonal Antibody
TRIP15 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody. Western blot 및 IHC(P)에서 사용 가능. 인간과 마우스 반응성, 비결합형 액상 형태로 제공되며, 안정적인 TBS 버퍼에 보관. 연구용으로만 사용.
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Thermo Fisher Scientific TRIP15 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3–5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (LNSLNQAVVSKLA) corresponding to the C-terminus amino acids of COPS2 (aa 431–443) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10981866 |
Product Specific Information
- Predicted to react with bovine, canine, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one utilizing NAD(+) and the other NADP(+).
Five isocitrate dehydrogenases have been reported:
- Three NAD(+)-dependent forms localized to the mitochondrial matrix
- Two NADP(+)-dependent forms (one mitochondrial, one cytosolic)
NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer composed of two alpha subunits, one beta subunit, and one gamma subunit.
The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-18161_TRIP15_P61201-1_Goat.svg, PA5-18161_TRIP15_P61201-1_Goat_PDP.jpeg)
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