Thermo Fisher Scientific ID2 Monoclonal Antibody (2C11)
ID2 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Western blot과 ELISA에 적합합니다. 인간 ID2 단백질을 면역원으로 사용하며, 액상 형태로 제공됩니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C11 |
| Immunogen | ID2 (AAH30639, 1–134 a.a) full-length recombinant protein with GST tag (MW of GST tag: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF PSELMSNDSK ALCG
Target Information
The inhibitor of DNA binding 2 (ID2) protein is essential for promoting the development of various cell types including natural killer cells, erythroid precursors, CD8+ and CD4+ T-cells. A lack of ID2 promotes B-cell development.
The chief role of this protein is to associate with ubiquitously expressed E proteins and other basic helix-loop-helix (HLH) family proteins, preventing them from binding to DNA and activating transcription. Activation of ID2 is critical for the development of the natural killer cell lineage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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