Thermo Fisher Scientific ID2 Monoclonal Antibody (3C3)
ID2 단백질을 인식하는 Mouse monoclonal antibody로, Western blot과 ELISA에 최적화되어 있습니다. 인간 시료에 반응하며, 비결합형 액상 형태로 제공됩니다. 연구용으로 세포 발달 및 ID2 관련 신호전달 연구에 적합합니다.
- 카탈로그번호
- H00003398-M01
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3C3 |
| Immunogen | ID2 (AAH30639, 1 a.a. – approximately 134 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF PSELMSNDSK ALCG
Target Information
The inhibitor of DNA binding 2 (ID2) protein is essential for promoting the development of various cell types, including natural killer cells, erythroid precursors, and CD8+/CD4+ T-cells. A lack of ID2 promotes B-cell development.
The primary role of ID2 is to associate with ubiquitously expressed E proteins and other basic helix-loop-helix (HLH) family proteins, preventing them from binding to DNA and activating transcription. Activation of ID2 is critical for the development of the natural killer cell lineage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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