Thermo Fisher Scientific PEG3 Monoclonal Antibody (OTI1E10)
Human PEG3 단백질을 인식하는 Mouse monoclonal antibody. Western blot 및 IHC(P)에서 검증됨. Affinity chromatography로 정제된 1 mg/mL 액상 제품. PBS/BSA/glycerol buffer에 보관하며, -20°C에서 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–364 of PEG3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724988 |
Target Information
In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5′ exons and a common promoter, and both genes are paternally expressed.
Alternative splicing events connect their shared 5′ exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3.
In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons.
Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis.
PEG3 has also shown tumor suppressor activity and involvement in tumorigenesis in glioma and ovarian cells.
Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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