Thermo Fisher Scientific CD278 (ICOS) Monoclonal Antibody (7E.17G9), PE, eBioscience
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
12-9942-82 | - | Thermo Fisher Scientific 12-9942-82 CD278 (ICOS) Monoclonal Antibody (7E.17G9), PE, eBioscience 100 ug pk | 재고문의 | pk | 333,000원 | - | 366,300원 | |
12-9942-81 | - | Thermo Fisher Scientific 12-9942-81 CD278 (ICOS) Monoclonal Antibody (7E.17G9), PE, eBioscience 50 ug pk | 재고문의 | pk | 201,000원 | - | 221,100원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Flow Cytometry (Flow)
0.25 µg/test
View 36 publications 36 publications
In vitro Assay (IV)
-
View 1 publication 1 publication
Product Specifications
Species Reactivity
Mouse
Published species
Human, Mouse
Host/Isotype
Rat / IgG2b, kappa
Recommended Isotype Control
Rat IgG2b kappa Isotype Control (eB149/10H5), PE, eBioscience™
Class
Monoclonal
Type
Antibody
Clone
7E.17G9
Conjugate
PE PE PE
View additional formats
- Unconjugated
- APC
- Biotin
- FITC
- Functional Grade
- PE-Cyanine5
- PE-Cyanine7
- PerCP-eFluor 710
- Super Bright 436
- Super Bright 645
- Request custom conjugation
Excitation/Emission Max
565/576 nm View spectra
Form
Liquid
Concentration
0.2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.09% sodium azide
Storage conditions
4° C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_466273
Product Specific Information
Description: The 7E.17G9 monoclonal antibody reacts with mouse ICOS (Inducible COStimulatory molecule), a T cell specific molecule and a third member of the CD28/CTLA-4 family. A homodimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response. ICOS binds to its ligand on activated APC including B cells called B7h/B7RP-1 and is thought to play a protective role in inflammatory autoimmune diseases. ICOS may be involved in the development of Th2 cells.
Applications Reported: The 7E.17G9 antibody has been reported for use in flow cytometric analysis.
Applications Tested: The 7E.17G9 antibody has been tested by flow cytometric analysis of Con A-stimulated mouse splenocytes. This can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
ICOS (CD278) encodes a protein that is a member of the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and has a crucial role in cell-cell signaling, immune responses, and the regulation of cell proliferation. ICOS has been linked to various disorders, including Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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