Thermo Fisher Scientific Claudin 19 Monoclonal Antibody (693202)
Human Claudin-19 단백질을 인식하는 Mouse Monoclonal Antibody로, IHC(P)에서 8–25 µg/mL로 사용 가능. Lyophilized 형태이며, PBS(5% trehalose) 버퍼에 재구성. 단백질 정제는 Protein A/G 방식으로 수행됨. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 8–25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 693202 |
| Immunogen | NS0 mouse myeloma cell line transfected with human Claudin-19 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606666 |
Product Specific Information
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space through calcium-independent cell-adhesion activity.
Defects in this gene cause hypomagnesemia renal with ocular involvement (HOMGO), a progressive renal disease characterized by magnesium wasting, hypomagnesemia, hypercalciuria, and nephrocalcinosis, often with ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, myopia, and nystagmus.
Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
[Provided by RefSeq, Jun 2010]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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