Thermo Fisher Scientific RASA3 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RASA3 (NP_031394.2, 1 a.a. approximately 834 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RASA3,uniProtId:Q14644-1,ncbiNodeId:9606,antigenRange:1-834,antigenLength:834,antigenImageFileName:H00022821-D01P_RASA3_Q14644-1_Rabbit.svg,antigenImageFileNamePDP:H00022821-D01P_RASA3_Q14644-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MAVEDEGLRV FQSVKIKIGE AKNLPSYPGP SKMRDCYCTV NLDQEEVFRT KIVEKSLCPF YGEDFYCEIP RSFRHLSFYI FDRDVFRRDS IIGKVAIQKE DLQKYHNRDT WFQLQHVDAD SEVQGKVHLE LRLSEVITDT GVVCHKLATR IVECQGLPIV NGQCDPYATV TLAGPFRSEA KKTKVKRKTN NPQFDEVFYF EVTRPCSYSK KSHFDFEEED VDKLEIRVDL WNASNLKFGD EFLGELRIPL KVLRQSSSYE AWYFLQPRDN GSKSLKPDDL GSLRLNVVYT EDHVFSSDYY SPLRDLLLKS ADVEPVSASA AHILGEVCRE KQEAAVPLVR LFLHYGRVVP FISAIASAEV KRTQDPNTIF RGNSLASKCI DETMKLAGMH YLHVTLKPAI EEICQSHKPC EIDPVKLKDG ENLENNMENL RQYVDRVFHA ITESGVSCPT VMCDIFFSLR EAAAKRFQDD PDVRYTAVSS FIFLRFFAPA ILSPNLFQLT PHHTDPQTSR TLTLISKTVQ TLGSLSKSKS ASFKESYMAT FYEFFNEQKY ADAVKNFLDL ISSSGRRDPK SVEQPIVLKE GFMIKRAQGR KRFGMKNFKK RWFRLTNHEF TYHKSKGDQP LYSIPIENIL AVEKLEEESF KMKNMFQVIQ PERALYIQAN NCVEAKDWID ILTKVSQCNQ KRLTVYHPSA YLSGHWLCCR APSDSAPGCS PCTGGLPANI QLDIDGDRET ERIYSLFNLY MSKLEKMQEA CGSKSVYDGP EQEEYSTFVI DDPQETYKTL KQVIAGVGAL EQEHAQYKRD KFKKTKYGSQ EHPIGDKSFQ NYIRQQSETS THSI

Target Information

Human GAP1-InsP4 BP, also designated Ras p21 protein activator (GTPase-activating protein) 3 [Ins(1,3,4,5)P4-binding protein], is an 829-amino acid protein that binds phospholipids in both a calcium-dependent and -independent manner. GAP1, one of the Ras GTPase-activating protein families, comprises four distinct genes, including GAP1(m), GAP1-InsP4 BP, MRASAL (murine Ras GTPase-activating-like) and KIAA0538. This family contains an N-terminal tandem C2 domain, a GAP-related domain and a C-terminal pleckstrin homology (PH) domain. The PH domains of GAP1-InsP4 BP are essential for membrane targeting via binding of specific phospholipids. Following agonist-stimulated PtdIns(3,4,5)P(3) production, group I family PH domain containing proteins like GAP1-InsP4 BP specifically bind inositol phosphates, which are subsequently targeted to the plasma membrane.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.