Thermo Fisher Scientific ESAM Polyclonal Antibody
Thermo Fisher Scientific의 ESAM Polyclonal Antibody는 인간 ESAM 단백질을 인식하는 염소 유래 다클론 항체입니다. Western blot, IHC, Flow Cytometry에 사용 가능하며, 높은 특이성과 낮은 교차 반응성을 제공합니다. 연구용으로 혈관 투과성 및 세포 접합 관련 연구에 적합합니다.
- 카탈로그번호
- PA547368
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 5–15 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human ESAM (Gln30–Ala247) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606178 |
Product Specific Information
- In direct ELISAs, approximately 5% cross-reactivity with recombinant mouse ESAM is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
ESAM is a 55-kDa membrane protein composed of two extracellular Ig domains, a single transmembrane domain, and a 120-amino-acid cytoplasmic domain.
It is related to the junctional adhesion molecule (JAM) family and is expressed on endothelial cells and activated platelets.
ESAM at endothelial tight junctions plays a role in regulating vascular permeability in response to agents such as VEGF or extravasating neutrophils.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-47368_ESAM_Q96AP7-1_Goat.svg, PA5-47368_ESAM_Q96AP7-1_Goat_PDP.jpeg)
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