Thermo Fisher Scientific DDX3 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human DDX3 protein. Validated for Western blot and immunoprecipitation. Supplied as liquid form at 1 mg/mL concentration. Recommended storage at 4°C, suitable for research use only.
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:5,000–1:15,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 550 and 600 of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
The protein encoded by this gene belongs to the DEAD-box protein family, characterized by the conserved Asp-Glu-Ala-Asp (DEAD) motif and ATP-dependent RNA helicase activity. It exhibits RNA-independent ATPase activity, stimulated by both RNA and DNA.
This protein functions in both the nucleus and cytoplasm, contributing to transcriptional regulation, mRNP assembly, pre-mRNA splicing, mRNA export, translation, cellular signaling, and viral replication.
Misregulation of this gene has been linked to tumorigenesis. A paralog exists on the Y chromosome, and pseudogenes with similarity are present on chromosome 4 and the X chromosome. Alternative splicing generates multiple transcript variants.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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