Thermo Fisher Scientific FNTB Polyclonal Antibody
Thermo Fisher Scientific의 FNTB Polyclonal Antibody는 인간 FNTB 단백질을 인식하는 Rabbit IgG 기반 항체로, WB, IHC, ICC/IF에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
- 카탈로그번호
- PA564061
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FNTB. Recombinant protein control fragment (Product #RP-103467) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641709 |
Product Specific Information
Immunogen sequence:
MASPSSFTYY CPPSSSPVWS EPLYSLRPEH ARERLQDDSV ETVTSIEQAK VEEK
Highest antigen sequence identity to the following orthologs:
- Mouse: 96%
- Rat: 98%
Target Information
Eukaryotic cells contain three types of prenyltransferases that attach either a farnesyl group (15 carbons) or a geranylgeranyl group (20 carbons) in thioether linkage to C-terminal cysteine residues in various proteins. These posttranslational modifications enable membrane localization of proteins lacking transmembrane domains.
CAAX farnesyltransferase (FTase) attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins ending in the CAAX box, where C is cysteine, A is usually an aliphatic amino acid, and X is typically methionine or serine.
The gene for the beta subunit of CAAX farnesyltransferase (FNTB) is located at 14q23–q24, identified by Southern blot hybridization, PCR analyses, and fluorescence chromosomal in situ hybridization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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