Thermo Fisher Scientific Rb Monoclonal Antibody (32C8)
Rb 단백질을 인식하는 Mouse Monoclonal Antibody (Clone 32C8). Western blot, ELISA, Immunoprecipitation에 사용 가능. 인간 샘플에 검증됨. 액상 형태로 -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/µL | View 1 publication |
| ELISA (ELISA) | Assay-dependent | - |
| Immunoprecipitation (IP) | 2 µg | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 32C8 |
| Immunogen | Recombinant human protein purified from E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_1960343 |
Product Specific Information
A suggested positive control for this product is U-2OS cells.
Target Information
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine residues, but not on tyrosine. It forms complexes with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. The Rb protein may regulate transcription, and loss of its function can lead to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of the breast, colon, prostate, kidney, nasopharynx, and leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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