Thermo Fisher Scientific Parvalbumin Polyclonal Antibody
Parvalbumin 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간 및 설치류 등 다양한 종에 반응합니다. Western blot, IHC, ICC, ELISA 등 다중 응용 가능하며, 고순도 Protein A 정제 및 안정적인 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from Parvalbumin Intermedial |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Parvalbumin (PV) is a calcium-binding protein expressed in specific muscle fibers and fast-firing neurons. It belongs to the EF-hand protein family and plays a critical role in calcium decay during muscle contraction and relaxation cycles. The rate of muscle relaxation correlates positively with parvalbumin concentration. PV is also expressed in specific GABAergic interneurons that help maintain excitation-inhibition balance in the cortex and hippocampus. In ALS patients, parvalbumin immunoreactivity is absent from neuron populations lost early in the disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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