Thermo Fisher Scientific SAPK4 Polyclonal Antibody
Human p38 delta/MAPK13 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, ELISA, IP 등 다양한 응용에 적합. 보존제가 없으며 고순도 정제. 세포 스트레스 및 염증 반응 연구용으로 최적화된 연구용 항체.
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 4–8 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human p38 delta/MAPK13 Protein (Met1–Leu365) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788069 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human p38 delta/MAPK13.
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase that transduces various extracellular signals, including cytokine and environmental stress responses. It regulates keratinocyte differentiation and is activated by environmental stresses and proinflammatory cytokines through phosphorylation or autophosphorylation mediated by MAP3K7IP1/TAB1.
Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, indicating roles in stress-related transcription, cell cycle regulation, and genotoxic stress response.
Four alternatively spliced transcript variants of SAPK4 encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-80793_SAPK4_O15264-1_Rabbit.svg, PA5-80793_SAPK4_O15264-1_Rabbit_PDP.jpeg)
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