Thermo Fisher Scientific GPSM2 Polyclonal Antibody

Product Specifications

Product Specific Information

Immunogen sequence:
REVGDKSGEL TARLNLSDLQ MVLGLSYSTN NSIMSENTEI DSSLNGVRPK LGRRHSMENM
ELMKLTPEKV QNWNSEILAK QKPLIAKPSA KLLFVNRLKG KKYKTNSSTK VLQDASNSID
HRIPNSQRKI SADTIGDEGF FDL

Sequence identity with orthologs:

• Mouse: 88%
• Rat: 81%

Target Information

The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of Leu-Gly-Asn repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.