Thermo Fisher Scientific Tankyrase 2 Polyclonal Antibody
Tankyrase 2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 Polyclonal 항체로, Western blot에 적합합니다. 인간에 반응하며 개와 마우스에도 예측 반응합니다. 0.5 mg/mL 농도의 액상 형태로, TBS(pH 7.3) 버퍼에 0.5% BSA 및 0.02% sodium azide가 포함되어 있습니다.
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–1.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (HRRKEVSEENHNH) corresponding to the internal amino acids of TNKS2 (aa 1011–1024) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10983627 |
Product Specific Information
- This antibody is predicted to react with canine and mouse based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 16,000.
Target Information
Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length regulation, and vesicle trafficking.
Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, key components of the β-catenin destruction complex.
Also mediates poly-ADP-ribosylation of BLZF1, CASC3, and TERF1, contributing to telomere maintenance and proteasome activity regulation.
[Source: UniProt]
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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