Thermo Fisher Scientific Phospho-NFKB p65 (Thr435) Polyclonal Antibody
NFkB p65 Thr435 인산화 부위를 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 반응성. Western blot, IHC, ICC, Flow cytometry, ELISA 등 다양한 응용에 적합. 고순도 Protein A 정제, 안정적 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific Phospho-NFKB p65 (Thr435) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human NFKB p65 around the phosphorylation site of Thr435 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Nuclear factor kB p65 (NF-kB p65), encoded by the RELA gene on chromosome 11 in humans, is also known as RelA. It is a member of the Rel protein family and forms heterodimers with p50 or p52 subunits to constitute NF-kB (Nuclear factor kappa-light-chain-enhancer of activated B cells). Upon TNFα receptor binding, IKK is phosphorylated, which subsequently phosphorylates IκB, leading to its proteasomal degradation. NF-kB p65 plays a critical role in transcription regulation of the immunoglobulin κ gene in mature B-lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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