Thermo Fisher Scientific DDR2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA0978)
DDR2 단백질을 인식하는 알파카 유래 재조합 단일클론 항체. ELISA에 적합하며 CHO 세포에서 발현됨. 금속 킬레이트 크로마토그래피로 정제된 액상 항체로, 1 mg/mL 농도 유지. 연구용으로만 사용 가능.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA0978 |
| Immunogen | Recombinant Human CD167b/DDR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
DDR2 is a member of a subclass of receptor tyrosine kinases (RTKs) and contains a distinct extracellular region encompassing a factor VIII-like domain. DDR1 and DDR2 are potently inhibited by Gleevec. DDR2 is required for normal bone development and regulates osteoblast differentiation and chondrocyte maturation via a MAP kinase–dependent signaling pathway leading to activation of RUNX2. It regulates extracellular matrix remodeling by up-regulating collagenases MMP1, MMP2, and MMP13, facilitating cell migration and tumor invasion. DDR2 also promotes fibroblast migration and proliferation, contributing to cutaneous wound healing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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