Thermo Fisher Scientific Protein S Polyclonal Antibody
Human Protein S를 인식하는 Rabbit Polyclonal Antibody로, Western Blot과 IHC(Paraffin)에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이도와 재현성을 제공. 액상 형태, 0.1 mg/mL 농도, PBS 및 글리세롤 버퍼에 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human Protein S. Recombinant protein control fragment (Product # RP-100455) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856148 |
Product Specific Information
Immunogen sequence:
QGASGIKEII QEKQNKHCLV TVEKGSYYPG SGIAQFHIDY NNVSSAEGWH VNVTLNIRPS TGTGVMLALV SGNNTVPFAV SLVDSTSEKS QDILLSVENT VIYRIQALSL CSDQQSHLEF RVNR
Target Information
Protein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. It has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of Protein S in human plasma is about 25 µg/mL, with a half-life of approximately two days. About 40% of Protein S in plasma exists in a free form, while 60% is complexed with C4b-binding Protein (C4BP). Only the free Protein S functions as a cofactor to antigen-presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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