Thermo Fisher Scientific IL17B Polyclonal Antibody
마우스 IL-17B를 인식하는 Goat Polyclonal Antibody로, WB, Flow, ELISA, Neutralization에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. 인간 IL-17B와 약 40% 교차 반응. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
| ELISA (Detection) | 0.1–0.4 µg/mL |
| ELISA (Capture) | 0.2–0.8 µg/mL |
| Neutralization (Neu) | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant mouse IL-17B (His21–Phe180) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2576811 |
Product Specific Information
- In sandwich ELISAs, approximately 40% cross-reactivity with recombinant human IL-17B is observed.
- Less than 0.3% cross-reactivity with recombinant mouse IL-17, IL-17C, IL-17D, IL-17E, and IL-17F.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level: <0.10 EU per 1 µg of antibody (LAL method).
Target Information
The protein encoded by this gene is a T cell-derived cytokine sharing sequence similarity with IL-17. It stimulates release of TNF alpha (TNF) and IL1 beta (IL1B) from monocytic cells. Immunohistochemical analysis indicates localization primarily in neuronal cell bodies of several nerve tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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