Thermo Fisher Scientific PDGF-B Polyclonal Antibody
PDGF-B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 등 다양한 응용에 적합. 고순도(>95%) 항원 친화 크로마토그래피로 정제. 인간, 마우스, 랫트 반응성. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 21–70 of Human PDGF-B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2802989 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF).
The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize or heterodimerize with the related PDGF subunit A.
These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes.
Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, where this gene and the collagen type 1 alpha 1 gene are located, are linked to dermatofibrosarcoma protuberans, a rare skin tumor.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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