ELK Biotechnology HDAC2 rabbit pAb
HDAC2 단백질을 인식하는 토끼 다클론 항체로, Western blot, IHC, IF, ELISA에 사용 가능. 인간, 마우스, 랫, 원숭이에 반응. 핵 및 세포질에 위치하며 히스톤 탈아세틸화 효소 연구에 적합. -20°C에서 1년 보관 가능.
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HDAC2 rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | HDAC2; Histone deacetylase 2; HD2 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human HDAC2 (AA range: 360–409) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 55 kD |
| GeneID (Human) | 3066 |
| Human Swiss-Prot No | Q92769 |
| Cellular Localization | Nucleus, Cytoplasm |
| Species Reactivity | Human, Mouse, Rat, Monkey |
Background
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3, and H4).
This protein forms transcriptional repressor complexes by associating with various proteins, including YY1, a mammalian zinc-finger transcription factor. It plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternative splicing results in multiple transcript variants.
[provided by RefSeq, Apr 2010]
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