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ELK Biotechnology GRP1 rabbit pAb
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GRP1 단백질을 인식하는 토끼 폴리클로날 항체로 WB와 ELISA에 적합합니다. 인간 유래 합성 펩타이드로 면역화되었으며, 세포질 및 세포막에 위치한 GRP1 단백질 검출에 사용됩니다. -20°C에서 1년간 보관 가능합니다.
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ELK Biotechnology ES2482-100UL GRP1 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES2482-50UL GRP1 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology GRP1 rabbit pAb
ELK Biotechnology GRP1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | GRP1 rabbit pAb |
| Alternative Names | CYTH3; ARNO3; GRP1; PSCD3; Cytohesin-3; ARF nucleotide-binding site opener 3; Protein ARNO3; General receptor of phosphoinositides 1; Grp1; PH; SEC7 and coiled-coil domain-containing protein 3 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GRP1. AA range: 351-400 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 46 kD |
| GeneID (Human) | 9265 |
| Human Swiss-Prot No | O43739 |
| Cellular Localization | Cytoplasm, cytosol; Cell membrane; Peripheral membrane protein; Cell junction (adherens junction, tight junction). Translocates from the cytosol to membranes enriched in phosphatidylinositol 3,4,5-trisphosphate. |
| Species Reactivity | Human; Mouse; Rat; Monkey |
Background
This gene encodes a member of the PSCD (pleckstrin homology, Sec7, and coiled-coil domains) family. PSCD family members share a structural organization that includes an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain.
- The coiled-coil motif is involved in homodimerization.
- The Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity.
- The PH domain interacts with phospholipids and mediates membrane association.
Members of this family regulate protein sorting and membrane trafficking. The encoded protein plays a role in controlling Golgi structure and function and may regulate ADP-ribosylation factor protein 6 (ARF6) and ARF1 activity.
(Information provided by RefSeq, Jul 2008)
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