ELK Biotechnology GCN5 rabbit pAb
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| Product name: | GCN5 rabbit pAb |
| Alternative Names: | KAT2A; GCN5; GCN5L2; HGCN5; Histone acetyltransferase KAT2A; General control of amino acid synthesis protein 5-like 2; Histone acetyltransferase GCN5; HsGCN5; Lysine acetyltransferase 2A; STAF97 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human GCN5L2. AA range:691-740 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 100kD |
| GeneID（Human）: | 2648 |
| Human Swiss-Prot No: | Q92830 |
| Cellular localization: | Nucleus . Chromosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Mainly localizes to the nucleus (PubMed:27796307). Also localizes to centrosomes in late G1 and around the G1/S transition, coinciding with the onset of centriole formation (PubMed:27796307). . |
| Background: | KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009], |
| Species Reactivity: | Human;Mouse |
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