ELK Biotechnology Gads rabbit pAb
GRAP2 단백질을 인식하는 토끼 다클론 항체로, Western blot 및 ELISA에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며, 세포 내핵·세포질·엔도솜에 발현된 단백질 검출에 유용합니다. -20°C에서 1년 보관 가능합니다.
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제품명
Gads rabbit pAb
제품 개요
Gads(GRAP2) 단백질을 인식하는 토끼 다클론 항체로, GRB2/Sem5/Drk 패밀리에 속하는 어댑터 단백질 연구에 사용됩니다. 본 항체는 인간 GRAP2 유래 합성 펩타이드(AA 121–170)에 대해 제작되었습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | GRAP2; GADS; GRB2L; GRID; GRB2-related adapter protein 2; Adapter protein GRID; GRB-2-like protein; GRB2L; GRBLG; GRBX; Grf40 adapter protein; Grf-40; Growth factor receptor-binding protein; Hematopoietic cell-associated adapter protein Grp |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human GRAP2 (AA range: 121–170) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 38 kDa |
| Gene ID (Human) | 9402 |
| Human Swiss-Prot No. | O75791 |
| Cellular Localization | Nucleus, Cytoplasm, Endosome |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
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