ELK Biotechnology EphA1 rabbit pAb
EphA1 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 생쥐, 랫트 시료에 반응. 세포막 단백질 검출에 적합하며, 고순도 IgG 형태로 제공. -20°C에서 1년 보관 가능.
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EphA1 rabbit pAb
제품 개요
EphA1 단백질을 인식하는 토끼 폴리클로날 항체로, ephrin 수용체 서브패밀리에 속하는 단백질-티로신 키나아제 계열 단백질 연구에 사용됩니다. 신경계 발달 및 암세포 관련 연구에 유용합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | EphA1 rabbit pAb |
| Alternative Names | EPHA1; EPH; EPHT; EPHT1; Ephrin type-A receptor 1; hEpha1; EPH tyrosine kinase; EPH tyrosine kinase 1; Erythropoietin-producing hepatoma receptor; Tyrosine-protein kinase receptor EPH |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human EPHA1 (AA range: 541–590) |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 108 kDa |
| Gene ID (Human) | 2041 |
| Human Swiss-Prot No. | P21709 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Rat; Mouse |
| Storage | -20°C, 1 year |
Background
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors are involved in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and two fibronectin type III repeats. The ephrin receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. (RefSeq, Jul 2008)
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