Thermo Fisher Scientific HDAC10 (near N-terminus) Polyclonal Antibody
HDAC10 단백질의 N-말단 부위를 타겟으로 한 Rabbit Polyclonal Antibody로, WB, IHC, ELISA, IP 등 다양한 응용 가능. 인간 HDAC10에 특이적이며, 액상 형태로 제공되고 -20°C에서 안정적 보관 가능. 연구용으로만 사용.
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Thermo Fisher Scientific HDAC10 (near N-terminus) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Anti-HDAC10 affinity purified antibody prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide near the N-terminus of human HDAC10 protein (UniProt ID: Q969S8-1, Antigen range: 1–669). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 30% glycerol, 0.15M NaCl |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
Stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
A BLAST analysis suggests cross-reactivity with human HDAC10 based on 100% sequence homology. Cross-reactivity with HDAC10 from other species has not been determined.
Target Information
HDAC10 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4). Histone deacetylation acts as a tag for epigenetic repression and plays a crucial role in transcriptional regulation, cell cycle progression, and developmental processes.
Histone deacetylases function through the formation of large multiprotein complexes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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