Thermo Fisher Scientific SERPINB7 Polyclonal Antibody
Human SerpinB7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 1 mg/mL 농도의 액상 형태로 제공. 단기 보관은 4°C, 장기 보관은 -20°C에서 권장. 연구용으로만 사용 가능.
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Thermo Fisher Scientific SERPINB7 Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 12–265 of Human SerpinB7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549409 |
Product Specific Information
- Recommended positive control: NT2D1
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Megsin (SerpinB7, TP55) is a 380 amino acid cytoplasmic protein predominantly expressed in mesangial cells, which are essential for maintaining glomerular structure and function. As a member of the serpin family, megsin acts as a serine protease inhibitor, potentially inactivating MMP-2, MMP-9, and plasmin—proteins responsible for extracellular matrix degradation. Overexpression of megsin increases mesangial cell numbers and leads to mesangial matrix expansion with immune complex deposition, suggesting its involvement in renal structure regulation and various nephropathies.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
Usage
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-31936_SERPINB7_O75635-1_Rabbit.svg, PA5-31936_SERPINB7_O75635-1_Rabbit_PDP.jpeg)
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