Thermo Fisher Scientific OAZ3 Polyclonal Antibody
OAZ3 단백질을 인식하는 Thermo Fisher의 Rabbit Polyclonal 항체로, Western Blot에 최적화되어 있습니다. 인간 시료에 반응하며, Affinity chromatography로 정제된 액상 형태입니다. 세포 성장과 분열 조절 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human OAZ3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2689023 |
Product Specific Information
This target displays homology in the following species:
Cow: 86% • Dog: 93% • Guinea Pig: 86% • Horse: 93% • Human: 100% • Mouse: 100% • Pig: 93% • Rabbit: 93% • Rat: 93%
Target Information
The antizyme family is a group of small proteins that regulate cell growth and division by controlling the biosynthesis of polyamines such as putrescine, spermidine, and spermine.
AZ3, also known as OAZ3 (Ornithine decarboxylase antizyme 3), is a 187-amino-acid protein belonging to the ODC antizyme family.
It likely plays a key role in spermatogenesis by regulating intracellular polyamine concentrations in haploid germ cells through binding and destabilizing ornithine decarboxylase.
Mutations in the AZ3 gene are not a common cause of male infertility, and the normal AZ3 protein does not accelerate ornithine decarboxylase degradation.
AZ3 expression begins sharply in early spermatids, peaks in later stages, and disappears in spermatozoa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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