Thermo Fisher Scientific Phospho-Somatostatin Receptor 3 (Thr348) Polyclonal Antibody
Phospho-Somatostatin Receptor 3 (Thr348) 폴리클로날 항체로 인간 SSTR3 인산화 부위를 인식. Western blot에 적합하며 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 4°C 또는 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: Not applicable (N/A)
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human SST3 around the phosphorylation site of Thr348 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Expression of Somatostatin Receptor Type 3 (SSTR3) has been reported in brain, breast, eye, gastrointestinal tract, pancreas, and thyroid.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist.
All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms.
Activating ligands influence GPCR conformation, leading to signaling via G-proteins and downstream effectors.
Studies have revealed mechanisms of negative regulation of GPCRs, which have major implications for cellular physiology and pharmacological research.
Notable GPCR-targeted drugs include Zyprexa (Eli Lilly) and Claritin (Schering-Plough).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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