Thermo Fisher Scientific MSH3 Polyclonal Antibody
Thermo Fisher Scientific의 MSH3 Polyclonal Antibody는 인간 MSH3 단백질을 인식하는 토끼 유래 다클론 항체입니다. Western blot과 Immunoprecipitation에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1025 to 1075 of human DNA mismatch repair protein Msh3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches and initiates DNA repair. The MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs, recognizing large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, it forms a ternary complex with the MutL alpha heterodimer, directing downstream MMR events including strand discrimination, excision, and resynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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