Thermo Fisher Scientific VAV3 Polyclonal Antibody
VAV3 단백질을 표적하는 Thermo Fisher Scientific의 토끼 유래 다클론 항체입니다. Western blot, ICC/IF, ELISA에 적합하며 인간 및 생쥐 시료 반응성이 있습니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 연구용으로 사용됩니다.
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Thermo Fisher Scientific VAV3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 560–680 of human VAV3 (NP_0061044) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806069 |
Product Specific Information
Immunogen sequence:
DNCGRVNSGE QGTLKLPEKR TNGLRRTPKQ VDPGLPKMQV IRNYSGTPPP ALHEGPPLQL QAGDTVELLK GDAHSLFWQG RNLASGEVGF FPSDAVKPCP CVPKPVDYSC QPWYAGAMER L
Positive Samples: Jurkat, Mouse brain, Mouse lung, Mouse spleen
Target Information
The VAV3 gene belongs to the VAV family and encodes guanine nucleotide exchange factors (GEFs) for Rho family GTPases. These proteins activate pathways involved in actin cytoskeletal rearrangements and transcriptional regulation. VAV3 acts as a GEF mainly for RhoG and RhoA, and less for RAC1, interacting preferentially with nucleotide-free states of these GTPases. Alternative splicing produces different isoforms.
Safety Information
⚠ WARNING: This product contains chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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