Thermo Fisher Scientific GPATCH3 Polyclonal Antibody
Human GPATCH3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. GPATCH3 관련 전사 조절 및 항바이러스 반응 연구에 적합.
- 카탈로그번호
- PA556918
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GPATCH3. Recombinant protein control fragment (Product # RP-94564) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642133 |
Product Specific Information
Immunogen sequence:
PNSALIPTDP AAEGQLLSQT SATDVRPLST RDSTPIQTRT CCCVISVRGL AQAQRLIRMY SGRRWLDSHG TWLPGRCLIR RLRLPTEASG LGSFPFKTRK EL
Sequence identity to orthologs:
- Mouse: 73%
- Rat: 72%
Target Information
Gene: GPATCH3
GPATCH3 is a protein-coding gene involved in transcriptional regulation. It activates transcription from the CXCR4 promoter and may control neural crest cell migration involved in ocular and craniofacial development. It also acts as a negative regulator of immune antiviral response by down-regulating RIG-I-like receptor signaling and inhibiting type I interferon production. The mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins such as TBK1 and TRAF6.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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