Thermo Fisher Scientific Phospho-NTAL (Tyr136) Polyclonal Antibody
Phospho-NTAL (Tyr136) 항체는 인간, 생쥐, 랫트 시료에서 인산화된 NTAL을 특이적으로 검출합니다. Western blot에 최적화된 Rabbit Polyclonal IgG로, 1 mg/mL 농도의 액상 형태이며 PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용됩니다.
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Applications
Tested Application
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LAT2 (Accession Q9GZY6), corresponding to amino acid residues around phosphorylated Tyr136 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817402 |
Product Specific Information
Antibody detects endogenous levels of LAB only when phosphorylated at Tyr136.
Target Information
NTAL (Non-T cell Activation Linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells, and macrophages.
It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells.
However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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