Thermo Fisher Scientific CCL19/MIP-3 beta Polyclonal Antibody
CCL19/MIP-3 beta에 특이적인 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능하며, Protein A로 정제된 1 mg/mL 액상 항체입니다. -20°C 보관하며 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from mouse CCL19 (amino acids 26–108) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CCL19, also known as MIP-3 beta (Macrophage Inflammatory Protein 3 beta), is a member of the CC subfamily of chemokines. It is most closely related to CCL21, sharing 32% amino acid sequence homology. CCL19 and CCL21 are expressed mainly by stromal cells in T cell-rich zones of lymph nodes and are key mediators in the homeostatic trafficking of naive T cells and activated dendritic cells into secondary lymphoid organs. They also play roles in T cell priming, activation, and lymphocyte recruitment to inflamed tissues. Both signal via the CCR7 receptor expressed on T cells and mature dendritic cells. Notably, only CCL19 binding leads to receptor desensitization and internalization.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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