Thermo Fisher Scientific NANS Polyclonal Antibody
NANS 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot, IHC, ICC/IF에 적합합니다. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C 또는 -20°C에서 보관하며 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA531140
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 11–271 of Human NANS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548614 |
Product Specific Information
- Recommended positive control: HepG2
- Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (84%), Pig (98%), Chicken (93%), Bovine (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes an enzyme involved in the biosynthetic pathways of sialic acids. The encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, showing higher activity toward the Neu5Ac phosphate product. Expression in insect cells results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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