Thermo Fisher Scientific CD79a (B-Cell Marker) Monoclonal Antibody (ZL7-4)
CD79a 단백질을 인식하는 ZL7-4 클론의 마우스 단일클론 항체로, B세포 마커 검출에 적합. WB, IHC, ICC, Flow, ELISA 등 다양한 응용 가능. 인간 시료 반응성, 단백질 A/G 정제, PBS 버퍼에 4°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ZL7-4 |
| Immunogen | IgM complex isolated from Daudi cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD79a is a disulphide-linked heterodimer that includes the B29 (CD79b) polypeptide. It is a B lymphocyte antigen receptor component that associates with Ig-alpha and Ig-beta, essential for B-cell receptor expression and function.
CD79a appears at the pre-B cell stage and persists until the plasma cell stage, where it is found intracellularly. It is expressed in most acute leukemias of precursor B cell type, B cell lines, B cell lymphomas, and some myelomas, but not in myeloid or T cell lines.
Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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