Thermo Fisher Scientific TEM7 Monoclonal Antibody (197C193)
TEM7 단클론 항체(197C193)는 인간, 마우스, 랫트 시료에서 TEM7 단백질을 검출하는 데 사용됩니다. WB, IHC, ICC, IP 등 다양한 응용에 적합하며, Protein G로 정제된 액상 형태로 제공됩니다. 암 관련 혈관 내피세포 연구 및 TEM7 발현 분석에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:10–1:500 |
| Immunocytochemistry (ICC/IF) | 1:10–1:500 |
| Immunoprecipitation (IP) | 1:10–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 197C193 |
| Immunogen | Amino acids 409–425 (LQNNLSPKTKGTPVHLG) of human TEM7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2166232 |
Product Specific Information
MA1-91725 detects TEM7 from human samples.
Target Information
Using SAGE (Serial Analysis of Gene Expression) technology, St. Croix et al. identified 46 genes whose expression is elevated in tumor-associated endothelium. Nine of these, named Tumor Endothelial Markers (TEMs, TEM1–9), are prominently expressed in tumor endothelial cells but absent or barely detectable in normal ECs.
TEM7 (Tumor endothelial marker 7) transcripts are specifically expressed in endothelium of colorectal, lung, pancreatic, breast, and brain cancers. TEM7 expression is consistent in both primary and metastatic tumors. Other members (TEM1, 3, 4, 5, 8, and 9) exhibit similar expression patterns in lung and brain tumors and liver metastasis. These genes are also active during angiogenesis, providing valuable resources for research in human angiogenesis.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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