Thermo Fisher Scientific ZNF488 Polyclonal Antibody
Human ZNF488 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보존. 신경세포 및 희소돌기아교세포 분화 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZNF488. Recombinant protein control fragment (Product #RP-95522). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2650148 |
Product Specific Information
Immunogen sequence:
WRLSEPELGR GCKPVLLEKT NRLGPEAAVG RAGRDVGSAE LALLVAPGKP RPGKPLPPKT RGEQRQSAFT ELPRMKDRQV D
Highest antigen sequence identity to the following orthologs:
- Mouse: 33%
- Rat: 39%
Target Information
ZNF488 is a transcriptional repressor that plays a role in oligodendrocyte differentiation together with OLIG2. It mediates Notch signaling-activated formation of oligodendrocyte precursors, promotes differentiation of adult neural stem progenitor cells (NSPCs) into mature oligodendrocytes, and contributes to remyelination following nerve injury. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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