Thermo Fisher Scientific TNFRSF14 Monoclonal Antibody (OTI7D7), TrueMAB
인간 TNFRSF14 단백질을 인식하는 마우스 모노클론 항체로 Western blot에 적합합니다. 정제된 형태로 동결건조되어 있으며, 재구성 시 약 1 mg/mL 농도로 사용 가능합니다. PBS 버퍼에 8% 트레할로오스 포함, 보존제 무첨가. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7D7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 39–283 of human TNFRSF14 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TNFRSF14 is a member of the TNF-receptor superfamily and functions as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV glycoprotein D (gD) to TNFRSF14 facilitates viral entry. The cytoplasmic region of TNFRSF14 interacts with TRAF family members to mediate immune signaling pathways. Activation in T cells promotes proliferation and cytokine production, contributing to inflammation and enhanced CTL-mediated tumor immunity. Multiple alternatively spliced transcript variants exist, though some full-length forms remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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