Thermo Fisher Scientific IRAK-M Polyclonal Antibody
IRAK-M 단백질을 인식하는 Goat Polyclonal 항체로, Mouse와 Rat 시료에 반응. Western blot 및 Peptide ELISA에 적합. 액상 형태, 0.5 mg/mL 농도, TBS 버퍼에 0.5% BSA 포함. 연구용으로만 사용 가능.
- 카탈로그번호
- PA518963
- 판매단위
- pk
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Applications
- Western Blot (WB): 0.03–0.1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (GHSYGSKPMEKR) corresponding to internal amino acids of IRAK3 (aa 582–593) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10989185 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
IRAK3 (serine/threonine kinase, interleukin-1 receptor-associated kinase 3) is a member of the interleukin-1 receptor-associated kinase protein family, essential for Toll/IL-R immune signal transduction.
Primarily expressed in monocytes and macrophages, IRAK3 functions as a negative regulator of Toll-like receptor signaling.
It mediates critical aspects of innate immunity, leading to immunocompromised states during sepsis.
Mutations in IRAK3 are associated with susceptibility to asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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