Thermo Fisher Scientific ENG Monoclonal Antibody (3D5)
Human CD105(Endoglin)을 인식하는 Mouse monoclonal antibody (Clone 3D5). Western blot 및 ELISA에 적합하며, 비결합형 액상 형태로 제공. PBS buffer에 보존제 없이 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1–5 µg/mL
- ELISA: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3D5 |
| Immunogen | ENG (AAH14271, 27 a.a. approximately 658 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Target Family: CD105 (Endoglin), UniProt ID: P17813-1, Antigen Range: 1–658 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
TVHCDLQPVG PERDEVTYTT SQVSKGCVAQ APNAILEVHV LFLEFPTGPS QLELTLQASK QNGTWPREVL LVLSVNSSVF LHLQALGIPL HLAYNSSLVT FQEPPGVNTT ELPSFPKTQI LEWAAERGPI TSAAELNDPQ SILLRLGQAQ GSLSFCMLEA SQDMGRTLEW RPRTPALVRG CHLEGVAGHK EAHILRVLPG HSAGPRTVTV KVELSCAPGD LDAVLILQGP PYVSWLIDAN HNMQIWTTGE YSFKIFPEKN IRGFKLPDTP QGLLGEARML NASIVASFVE LPLASIVSLH ASSCGGRLQT SPAPIQTTPP KDTCSPELLM SLIQTKCADD AMTLVLKKEL VAHLKCTITG LTFWDPSCEA EDRGDKFVLR SAYSSCGMQV SASMISNEAV VNILSSSSPQ RKKVHCLNMD SLSFQLGLYL SPHFLQASNT IEPGQQSFVQ VRVSPSVSEF LLQLDSCHLD LGPEGGTVEL IQGRAAKGNC VSLLSPSPEG DPRFSFLLHF YTVPIPKTGT LSCTVALRPK TGSQDQEVHR TVFMRLNIIS PDLSGCTSKG LVLPAVLGIT FGAFLIGALL TAALWYIYSH TRSPSKREPV VAVAAPASSE SSSTNHSIGS TQSTPCSTSS MA
Target Information
CD105 (Endoglin)은 Type I transmembrane protein으로, 인간 혈관 내피세포에서 높게 발현됩니다. O- 및 N-glycosylated homodimer 형태로 존재하며, 종양 혈관 및 증식 세포에서 발현이 증가하는 것으로 알려져 있습니다. CD105는 TGF-β1 및 TGF-β3에 높은 친화도로 결합하지만 TGF-β2에는 결합하지 않습니다.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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