Thermo Fisher Scientific Ruplizumab Humanized Recombinant Human Monoclonal Antibody

Applications

• ELISA (ELISA): Assay-dependent

Product Specifications

Product Specific Information

• Endotoxin level < 0.01 EU/µg by LAL method
• Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
• Store at 2–8°C for one week.
• Store at -20 to -80°C for twelve months from the date of receipt.

Target Information

Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive pharmaceutical and is a component of Antova.
It is an anti-CD40L monoclonal antibody. The binding of CD40 to its ligand CD40L is a critical element in T cell activation.
In systemic lupus erythematosus, CD40L is over-expressed on T cells, B cells, and monocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.