Thermo Fisher Scientific Apolizumab Humanized Recombinant Human Monoclonal Antibody

Applications

• ELISA (ELISA): Assay-dependent

Product Specifications

Product Specific Information

• Endotoxin level < 0.01 EU/µg by LAL method
• Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
• Store at 2–8°C for one week.
• Store at -20 to -80°C for twelve months from the date of receipt.

Target Information

Apolizumab is a humanized monoclonal antibody that is being studied as a treatment for hematologic cancers. It is directed against 1D10, a polymorphic determinant on the HLA-DR beta chain expressed on normal and neoplastic B cells.
Apolizumab induces complement-mediated cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and apoptosis of 1D10 antigen-positive B cells in vitro.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.