
Thermo Fisher Scientific Apolizumab Humanized Recombinant Human Monoclonal Antibody
Apolizumab 인간화 단클론 항체로, HLA-DRB의 1D10 항원을 표적으로 하는 재조합 항체입니다. ELISA 등 연구용 분석에 사용되며, 단백질 A로 정제된 고순도 IgG1 항체입니다. 세포독성 및 세포매개 면역반응 연구에 적합합니다.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1 |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human HLA-DRB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.22 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2910840 |
Product Specific Information
- Endotoxin level < 0.01 EU/µg by LAL method
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week.
- Store at -20 to -80°C for twelve months from the date of receipt.
Target Information
Apolizumab is a humanized monoclonal antibody that is being studied as a treatment for hematologic cancers. It is directed against 1D10, a polymorphic determinant on the HLA-DR beta chain expressed on normal and neoplastic B cells.
Apolizumab induces complement-mediated cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and apoptosis of 1D10 antigen-positive B cells in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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